Paltrow made her acting debut on stage in 1990 and started appearing in films in 1991. She gained early notice for her work in films such as Se7en (1995), Emma (1996), in which she played the title role, and Sliding Doors (1998). She garnered worldwide recognition through her performance in Shakespeare in Love (1998), for which she won the Academy Award for Best Actress, a Golden Globe Award and two Screen Actors Guild Awards, for Outstanding Lead Actress and as a member of the Outstanding Cast. Since then, Paltrow has portrayed supporting as well as lead roles in films such as The Talented Mr. Ripley (1999), Shallow Hal (2001) and Proof (2005), for which she earned a Golden Globe nomination as Best Actress in Motion Picture Drama. In 2008, she appeared in the highest grossing movie of her career, the superhero film Iron Man, and then reprised her role as Pepper Potts in its sequel, Iron Man 2 (2010). Paltrow has been the face of Estée Lauder's Pleasures perfume since 2005.
| Movie | Untitled Avengers | Virginia "Pepper" Potts | 2019-04-24 |
| Movie | Avengers: Infinity War | Pepper Potts | 2018-04-25 |
| Movie | Spider-Man: Homecoming | Pepper Potts | 2017-07-05 |
| Series | Planet of the Apps | Herself | 2017-06-06 |
| Series | Carpool Karaoke | Herself | 2017-08-08 |
| Movie | Man in Red Bandana | Narrator | 2017-09-08 |
| Series | Chelsea | Herself | 2016-05-11 |
| Movie | Mortdecai | Johanna Mortdecai | 2015-01-21 |
| Movie | Marvel Studios: Assembling a Universe | Herself | 2014-03-18 |
| Movie | Iron Man 3 | Virginia "Pepper" Potts | 2013-04-18 |
| Movie | Iron Man 3 Unmasked | Herself | 2013-09-24 |
| Movie | The Avengers | Virginia "Pepper" Potts | 2012-04-25 |
| Movie | Thanks for Sharing | Phoebe | 2012-09-07 |
| Movie | Contagion | Beth Emhoff | 2011-09-08 |
| Movie | Glee: The Concert Movie | Holly Holliday | 2011-08-11 |
| Movie | Ultimate Iron Man: The Making of Iron Man 2 | Herself | 2010-09-28 |
| Movie | Iron Man 2 | Virginia "Pepper" Potts | 2010-04-28 |
| Movie | Country Strong | Kelly Canter | 2010-12-22 |
| Series | Glee | Holly Holliday | 2009-05-19 |
| Movie | The Victoria's Secret Fashion Show 2008 | Herself | 2008-02-02 |
| Series | Spain... on the Road Again | 2008-09-20 | |
| Movie | Iron Man | Virginia "Pepper" Potts | 2008-04-30 |
| Movie | Two Lovers | Michelle | 2008-11-19 |
| Movie | I Am Iron Man | Herself | 2008-09-30 |
| Movie | The Good Night | Dora Shaller | 2007-01-25 |
| Series | Movie Connections | Unknown | 2007-09-10 |
| Movie | Love and Other Disasters | Jacks | 2006-09-09 |
| Movie | Running with Scissors | Hope Finch | 2006-10-27 |
| Movie | Jay Z: Live at the Royal Albert Hall | Herself | 2006-11-21 |
| Movie | Infamous | Kitty Dean | 2006-11-16 |
| Movie | Proof | Catherine Llewellyn | 2005-09-05 |
| Movie | Sky Captain and the World of Tomorrow | Polly Perkins | 2004-09-17 |
| Movie | View from the Top | Donna | 2003-03-21 |
| Movie | Sylvia | Sylvia Plath | 2003-10-17 |
| Series | The Ellen DeGeneres Show | Unknown | 2003-09-08 |
| Series | American Idol | Unknown | 2002-06-11 |
| Movie | Austin Powers in Goldmember | Dixie Normous | 2002-07-26 |
| Movie | Possession | Maud Bailey | 2002-10-02 |
| Movie | The Anniversary Party | Skye Davidson | 2001-05-15 |
| Movie | The Royal Tenenbaums | Margot Tenenbaum | 2001-10-05 |
| Movie | Shallow Hal | Rosemary Shanahan | 2001-11-01 |
| Series | Clerks: The Animated Series | Unknown | 2000-05-31 |
| Movie | Duets | Liv | 2000-09-09 |
| Movie | Bounce | Abby Janello | 2000-11-15 |
| Movie | The Talented Mr. Ripley | Marge Sherwood | 1999-12-25 |
| Movie | Hush | Helen Baring | 1998-03-06 |
| Movie | Sliding Doors | Helen Quilley | 1998-04-23 |
| Movie | Great Expectations | Estella | 1998-01-19 |
| Movie | Shakespeare in Love | Viola De Lesseps | 1998-12-11 |
| Movie | A Perfect Murder | Emily Taylor | 1998-06-05 |
| Movie | Out of the Past | Sarah Orne Jewett (voice) | 1998-07-31 |
| Series | Thomas Jefferson | Jefferson's grandaughter (voice) | 1997-02-18 |
| Series | The View | Unknown | 1997-08-11 |
| Movie | The Pallbearer | Julie DeMarco | 1996-05-03 |
| Movie | Hard Eight | Clementine | 1996-02-28 |
| Series | The Daily Show with Trevor Noah | Unknown | 1996-07-22 |
| Movie | Emma | Emma Woodhouse | 1996-08-02 |
| Movie | Se7en | Tracy Mills | 1995-09-22 |
| Movie | Jefferson in Paris | Patsy Jefferson | 1995-03-31 |
| Movie | Moonlight and Valentino | Lucy Trager | 1995-09-29 |
| Series | Inside the Actors Studio | Unknown | 1994-06-01 |
| Movie | Mrs. Parker and the Vicious Circle | Paula Hunt | 1994-09-07 |
| Movie | Deadly Relations | Carol Ann Fagot Applegarth Holland | 1993-05-22 |
| Series | GMTV | Unknown | 1993-01-01 |
| Series | Late Night with Conan O'Brien | Unknown | 1993-09-13 |
| Movie | Malice | Paula Bell | 1993-09-29 |
| Movie | Flesh and Bone | Ginnie | 1993-11-05 |
| Series | Cruel Doubt | Angela Pritchard | 1992-05-17 |
| Movie | Shout | Rebecca | 1991-10-04 |
| Movie | Hook | Young Wendy | 1991-12-11 |
| Series | Live with Regis and Kathie Lee | Unknown | 1983-04-04 |
| Series | Saturday Night Live | Unknown | 1975-10-11 |
| Series | The Academy Awards | Gwyneth Paltrow | 1953-03-18 |